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Manahawkin Back Pain Related to Inflammation Reduced with Melatonin

Inflammation. Disc Degeneration. There is a connection. Inflammation acts as the body’s response system to damaging stimuli (injury, pathogens, metabolic stress – a disc herniation compressing a nerve!) as it tries to restore itself to normal before the harm was achieved. Manahawkin Chiropractic Center is never shocked at what the body can do! Manahawkin Chiropractic Center sees its Manahawkin chiropractic care as a partner of the body’s system in healing particularly when there is spine pain. Chiropractic care uses many tools like spinal manipulation, exercise, and nutrition to help the body. Melatonin is one nutritional tool that is showing value in its ability to interrupt the inflammatory process related disc herniation that brings about pain relief: back, neck, spine-related.

DISC DEGENERATION AND INFLAMMATION AND 'AUTOPHAGY'

Inflammatory markers interleukin-1β (IL-1β), interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) are related to intervertebral disc degeneration. (1) IL-1 β in fact promotes itself, its own expression, by upregulating NLRP3 inflammasome activation. (2) The body controls itself down to the cellular level via autophagy, the natural process via which the body’s cells clear out damaged (ie, by inflammation) or unneeded parts. In a recent study, melatonin increased autophagy and decreased the degradation of the disc’s extracellular matrix (technically indicated by a decrease in marker LC3B, autophagasomes and autolysosomes and inhibition of the NF-kB signaling pathway). The final conclusion was that melatonin prevents intervertebral disc degeneration by promoting autophagy. (3) Wow. Manahawkin Chiropractic Center is encouraged by this research to see just how well melatonin can work for Manahawkin back pain related to disc degeneration.

MELATONIN AND ITS HEALING WAYS FOR THE DISC

Disc degeneration is a very common malady seen at Manahawkin Chiropractic Center that positive news of melatonin’s benefits are quite rousing. A recent study described that melatonin could modify the extracellular matrix of the disc remodeling process initiated by IL-1 β. Further, melatonin decreased the inflammatory cell collection and reduced the release of linked inflammatory markers IL-1β, IL-6, and TNF-α. With this new discovery that melatonin interrupted the IL-1B feedback loop, researchers suggested that melatonin may contribute to the healing process of intervertebral discs after damage was already present. (1) Manahawkin Chiropractic Center continues following the new research regarding the role inflammation plays in Manahawkin disc degeneration and melatonin’s role in tackling it.

INFLAMMATION AND MELATONIN

The importance of melatonin in assisting to slow or stop painful conditions due to inflammation is growing. The description of melatonin as a multitasking molecule affecting mood, immunity, and energy among other mechanisms is quite appropriate. It’s also anti-oxidant, anti-aging, and anti-inflammatory, specifically by hindering the activation of inflammasomes (4) Melatonin’s formal chemical name is as about as long as its list of tasks: N-acetyl-5-methoxytryptamine. The pineal gland produces melatonin naturally. Melatonin influences the body’s aging, anti-inflammatory, anti-apoptosis (cell death), and autophagy (cell-cleanout) processes. (1) Melatonin’s specific influence on inflammation and disc degeneration is most interesting to Manahawkin Chiropractic Center and our Manahawkin back pain patients.

CONTACT Manahawkin Chiropractic Center

Listen to this PODCAST with Dr. Hrefna Sylvia based in Iceland where back pain isn’t much different from any other country on The Back Doctors Podcast with Dr. Michael Johnson as she describes how The Cox® Technic System of Spinal Pain Management handles disc degeneration for relief of chronic low back pain in her patient.

Schedule your Manahawkin chiropractic appointment with Manahawkin Chiropractic Center today. We can talk about how inflammation affects your back pain and how melatonin may address the related disc degeneration.

 
Manahawkin Chiropractic Center shares new findings that melatonin interrupts the inflammatory process in disc degeneration that causes back pain. 
 
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"This information and website content is not intended to diagnose, guarantee results, or recommend specific treatment or activity. It is designed to educate and inform only. Please consult your physician for a thorough examination leading to a diagnosis and well-planned treatment strategy. See more details on the DISCLAIMER page. Content is reviewed by Dr. James M. Cox I."